Amisha Parmar

A well-organized and extremely driven candidate with multidisciplinary research expertise is seeking a successful career in the pharmaceutical, biotech, or life science sectors with a sole purpose of improving quality of lives of people suffering from debilitating diseases, both independently and in tandem with a positive and problem solving attitude.

• Interdisciplinary Conference: from PAIN to SUFFERING, Humboldt University Festsaal, Berlin, Germany (May 24)
• SINS 2023 National Congress, Turin, Italy (Sep 23)
• SINS National Meeting of PhD Students in Neuroscience, Turin, Italy (Sep 23)
• Gordon Research Conference: Neurotrophic Mechanisms in Health and Disease. Newport (RI), United States (May - June 23)
• Motor Neuron Diseases: understanding the pathogenetic mechanisms to develop therapies (2nd Edition), Turin, Italy (Nov 22)
• ENCALS - European Network to Cure ALS, Edinburgh, Scotland (Jun 22)
• Virtual 32nd international symposium on ALS/MND, motor neuron disease association (Dec 21)
• Alzheimer's Research UK Conference (Mar 21)
• National Conference on New Paradigm in Toxicology held by Society of Toxicology (STOX), India at CSIR-IITR, Lucknow, U.P (Dec 12)
• National Symposium on Good Laboratory Practice (GLP) at PGIMER, Chandigarh (Jul 12)
• The 4th International Symposium on Drug Metabolism and Pharmacokinetics (DMPK) at NIPER, Mohali (Feb 12)
• The 61st Indian Pharmaceutical Congress, Ahmedabad (Dec 09)
• The 60th Indian Pharmaceutical Congress, New Delhi (Dec 08)

Laboratory mice handling and dosing (per-oral, ip, sc, im, intra-planter, intraarticular & iv), Blood and tissues collection, Surgeries, Stereotactic injection in mouse brain (Intracerebroventricular, Intracisterna magna), in vivo nerve conduction experiments (mice), DRG extraction and in vitro dorsal root ganglia primary cell culture, Genetically-modified Mouse colony management and genotyping, IVIS Spectrum in vivo imaging system, Incucyte neurotrack analysis, Incucyte live cell imaging, paraffin and cryo tissue embedding, Brightfield and Fluorescence microscopy, Western blotting, DNA-RNA isolation, PCR, RT-qPCR, Immunohistochemistry, immunofluorescence, immunocytochemistry, Biochemical estimations (MPO, GSH, MDA), ELISA, Single cell gel electrophoresis assay (Comet assay), Rotarod test, Novel Object Recognition Test, Mechanical allodynia (Von Frey test), Cold allodynia, Hyperalgesia (Hargreaves test), Motoric behavioural tests (gait analysis using Catwalk, neurological scoring), M.S. office tools (Word, PowerPoint, Excel), Image J, ChemiDoc-Image Lab, Graphpad prism, Reference Management software - Endnote, Meta-analysis: Gene Ontology Enrichment Analysis, Protein-Protein Interaction Analysis (STRING database), Gene Set Enrichment Analysis, Pathway analysis, Scientific data retrieval from various Internet portals like Springerlink, Science-direct, Pubmed, Google Scholar

Mentorship: supervised two summer internship students at UCLan, UK, Mentored undergraduate students in lab sessions at UCLan, UK, Trained Biotech Consortium India Limited (BCIL) sponsored internship candidate at Jubilant Biosys Ltd., Mentored a post-graduate research student in dissertation work on Anxiety and Depression at SDPARC, Tutored students in the neighborhood during career break, Bharuch, India (2013-2015); Scientific writing: worked as a freelancer with MP Advisors - Prepared a therapeutic report entitled, “Moderate to Severe Pain: Novel Abuse-Deterrent Formulation Technologies and Emergence of Novel Mechanisms in the Management of Pain” (2015); Self-motivation and Learning aptitude: During the Covid-19 pandemic when my university was closed, I independently learned R programming through the internet and gained proficiency in creating heatmaps and hierarchical clustering of quantitative data. Attended online courses to gain insights into transcriptomics and proteomics data analysis.

• Poster, The role of importin α3 in sensory neurons upon in vitro injury at SINS 2023 National Congress (Sep 14th – 17th), SINS National Meeting of PhD Students in Neuroscience (Sep 14th), Turin, Italy and Gordon Research Conference on Neurotrophic Mechanisms in Health and Disease (May 28th – June 2nd) Newport (RI), United States
• Poster, Histological characterization and expression of GSK-3beta and immediate-early genes in a new conditional knockout mouse model relevant to Alzheimer’s disease, Alzheimer’s Research UK Conference 2021, United Kingdom
• Oral, Alzheimer’s disease-related molecular mechanisms controlled by the transcription factor REST in the brain, Alzheimer’s Research UK NorthWest Science Day, UK (Jan 21)
• Poster, Studies on the testicular toxicity in dextran sulfate sodium-induced ulcerative colitis in mice, 32nd Annual Conference of Society of Toxicology (STOX) held at IITR-Lucknow, U.P (Dec 12)

• Neural Circuit Development and Plasticity, 5 days, 07/23, Utrecht Summer school, Utrecht, The Netherlands
• Statistical Methods for Research - Biomedical Sciences, Epigeum Online Course System, https://courses.epigeum.com/programme?id=55
• Molecular Biology Training Program, 15 days, 10/16, Rapture Biotech, Noida, India, Gel electrophoresis, Western blotting, PCR and RT-qPCR, DNA-RNA isolation
• Research training at the Department of Cell Biology, 08/16 to 10/16, Dabur Research Foundation, Ghaziabad, India, In-vitro cell culture: Maintenance of cancer cell lines: Cell reviving, sub-culturing and cryopreservation, Ex-vivo tissue culture: Selenite-induced cataract model
• Industrial program in Pharma Regulatory Affairs, 05/12 to 04/13, Bioinformatics Institute of India, Noida, India

Conferences

• Interdisciplinary conference: from PAIN to SUFFERING, Humboldt University Festsaal, Berlin, Germany (May 24)
• SINS 2023 National Congress, Turin, Italy (Sep 23)
• SINS National Meeting of PhD Students in Neuroscience, Turin, Italy (Sep 23)
• Gordon Research Conference: Neurotrophic Mechanisms in Health and Disease. Newport (RI), United States (May - June 23)
• Motor Neuron Diseases: understanding the pathogenetic mechanisms to develop therapies (2nd Edition), Turin, Italy (Nov 22)
• ENCALS - European Network to Cure ALS, Edinburgh, Scotland (Jun 22)
• Virtual 32nd international symposium on ALS/MND, motor neuron disease association (Dec 21)
• Alzheimer’s Research UK Conference (Mar 21)
• National Conference on New Paradigm in Toxicology held by Society of Toxicology (STOX), India at CSIR-IITR, Lucknow, U.P (Dec 12)
• National Symposium on Good Laboratory Practice (GLP) at PGIMER, Chandigarh (Jul 12)
• The 4th International Symposium on Drug Metabolism and Pharmacokinetics (DMPK) at NIPER, Mohali (Feb 12)
• The 61st Indian Pharmaceutical Congress, Ahmedabad (Dec 09)
• The 60th Indian Pharmaceutical Congress, New Delhi (Dec 08)

Laboratory mice/rats handling, dosing (per-oral, ip, sc, im, intra-planter, intraarticular & iv), blood and tissues collection, Stereotactic injection (Intracerebroventricular, Intracisterna magna), surgeries, Dorsal Root Ganglia extraction and In vitro primary cell culture, In vivo electrophysioloy (mice), Genetically-modified Mouse colony management and genotyping, IVIS Spectrum in vivo imaging, Neurite length (neurotrack software) analysis, Sartorius incucyte imaging, Paraffin and cryo tissue embedding, Brightfield and fluorescence microscopy, Western blotting, DNA-RNA isolation, PCR, RT-qPCR, Immunohistochemistry, immunofluorescence, immunocytochemistry, Biochemical estimations (MPO, GSH, MDA), ELISA, Genotoxicity assays-Single cell gel electrophoresis assay (Comet assay), Rotarod test, Novel Object Recognition Test, Mechanical allodynia (Von Frey test), Cold allodynia (acetone test), Hyperalgesia (Hargreaves test), Motoric behavioural tests (gait analysis using Catwalk, neurological scoring), M.S. office tools (Word, PowerPoint, Excel), Image J, ChemiDoc-Image Lab, Graphpad prism, Reference Management Software (Endnote Plus), Basic user of R, Biorender, Meta-analysis: Gene Ontology Enrichment Analysis, Protein-Protein Interaction Analysis (STRING database), Gene Set Enrichment Analysis, Pathway analysis, Scientific data retrieval from various Internet portals like Springerlink, Science-direct, Pubmed, Google Scholar

Supervised two summer internship (2020) students at UCLan, UK, Mentored undergraduate students in lab sessions (2020) at UCLan, UK, a Biotech Consortium India Limited (BCIL) sponsored internship candidate (master's level) at Jubilant Biosys Ltd. (2018), a post-graduate research student on dissertation work in Anxiety and Depression (2016) at SDPARC. Tutored students in the neighbourhood during career break (2013-2015) in India. Worked as a freelancer with MP Advisors - prepared a therapeutic report entitled, “Moderate to Severe Pain: Novel Abuse-Deterrent Formulation Technologies and Emergence of Novel Mechanisms in the Management of Pain” (2015), Self-motivation and Learning aptitude : Qualified Graduate Record Examination (GRE) with a score of 310/340 (2014), 6 months of university closure during Covid-19 pandemic (2020), I independently learned R programming through the internet and gained proficiency in creating heatmaps and hierarchical clustering of quantitative data. Attended online courses and gained insights into transcriptomics and proteomics data analysis. Planning and time management : planned thesis research project and produced data in time, produced a research paper.

• Awarded with a PhD scholarship at University of Turin, Italy (Jul 22)
• Awarded with £1000 international bursary, £2000 merit scholarship, and £3000 school contribution towards bench fees for MSc (by Research) program at University of Central Lancashire (Jan 20 – Mar 21)
• Awarded with “A Certificate of Appreciation” by Jubilant Biosys Ltd., Bangalore “For demonstrating exemplary performance and making a valuable contribution to the company” (Feb 2018)
• Achieved all India rank 22 in NIPER Ph.D. – 2018 entrance exam.
• Post-graduate Research Scholarship awarded by Ministry of Chemical and Fertilizers, Government of India to pursue Master of Science (Pharm.) at NIPER, Mohali.
• Qualified GPAT- 2011 (national level) entrance exam conducted by MS University, and NIPER-JEE-2011 (national level) entrance exam conducted by NIPER, Mohali, India

• Poster, The role of Importin α3 in sensory neurons upon in vitro injury – at SINS 2023 National Congress (Sep 23), SINS National Meeting of PhD Students in Neuroscience (Sep 23), Turin, Italy, and Gordon Research Conference on Neurotrophic Mechanisms in Health and Disease (May 23) Newport (RI), United States.
• Poster, Histological characterization and expression of GSK-3beta and immediate-early genes in a new conditional knockout mouse model relevant to Alzheimer's disease , Alzheimer's Research UK Conference 2021, UK
• Oral, Alzheimer's disease-related molecular mechanisms controlled by the transcription factor REST in the brain , Alzheimer's Research UK NorthWest Science Day, UK (Jan 21)
• Poster, Studies on the testicular toxicity in dextran sulfate sodium-induced ulcerative colitis in mice , 32nd Annual Conference of Society of Toxicology (STOX) held at IITR-Lucknow, U.P (Dec 12)

• Neural Circuit Development and Plasticity, 5 days, 07/23, Utrecht Summer school, Utrecht, The Netherlands
• Statistical Methods for Research - Biomedical Sciences, Epigeum Online Course System
• Molecular Biology Training Program, 15 days, 10/16, Rapture Biotech, Noida, India
• Research training at the Department of Cell Biology, 08/16 to 10/16, Dabur Research Foundation, Ghaziabad, India (In vitro cell culture, Ex-vivo tissue culture: Selenite-induced cataract model)
• Industrial program in Pharma Regulatory Affairs, 05/12 to 04/13, Bioinformatics Institute of India, Noida, India